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Therefore, urolithin A may offer a potential dual benefit to muscle health during ageing by improving both mitochondrial function and attenuating age-related chronic inflammation

Meanwhile, mitochondrial damage mediated by PCD protein 2 can increase the generation of mitochondrial reactive oxygen species, synergistically inducing autophagy and ferroptosis [113]

Alzheimers disease: the amyloid Cascade hypothesis

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Nitric oxide upregulates microglia phagocytosis and increases transient receptor potential vanilloid type 2 channel expression on the plasma membrane

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